Recombinant protein (or fragment).This information is considered to be commercially sensitive.
克隆号
ARC54525
产品形式
Liquid
偶联物
ABflo® 594. Ex:588nm. Em:604nm.
克隆号
ARC54525
产品形式
Liquid
偶联物
ABflo® 594. Ex:588nm. Em:604nm.
细胞定位
Cell surface, External side of plasma membrane.
存储缓冲液
Store at 2-8℃. Avoid freeze. Buffer: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
CD8+ T cells were initially isolated from fresh C57BL/6 mouse splenocytes using anti-CD8 rabbit monoclonal antibody (A23904). CD8+ T cells were activated for 2 days by anti-CD3 and CD28 antibodies, Activated CD8+ T cells demonstrated elevated expression of CD25 (left panel) and CD69 (right panel) using flowcytometry. ABflo® 594-conjugated anti-CD25 rabbit monoclonal antibody (A23809) and ABflo® 488-conjugated anti-CD69 rabbit monoclonal antibody (A24938) were used in flowcytometry assays.
Enables interleukin-2 binding activity and interleukin-2 receptor activity. Acts upstream of or within several processes, including Notch signaling pathway; activation-induced cell death of T cells; and regulation of T cell proliferation. Located in external side of plasma membrane. Is expressed in bone marrow. Used to study Sjogren's syndrome and inflammatory bowel disease. Human ortholog(s) of this gene implicated in immunodeficiency 41; lymphopenia; multiple sclerosis; type 1 diabetes mellitus; and type 1 diabetes mellitus 10. Orthologous to human IL2RA (interleukin 2 receptor subunit alpha).
