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Rabbit anti-Human TNF RII/TNFRSF1B mAb (RMK0235)

This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.

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货号: RMK0235
促销价:   ¥2100
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详细信息

产品名称
Rabbit anti-Human TNF RII/TNFRSF1B mAb
货号
RMK0235
免疫原
Recombinant Human TNF RII/TNFRSF1BProtein
纯化方式
Affinity purification
同种型
Rabbit IgG
存储溶液
Supplied as a 0.2um filtered solution in PBS,PH 7.4 containing Human TNF RII/TNFRSF1B Antibody.
CrossReactivity
/
存储条件
Store at -20℃. Avoid freeze / thaw cycles. Preservative:0.05%ProClin 300.Avoid repeated freeze-thaw cycles.

* This package insert must be read in its entirety before using this product.

应用

Human TNFRSF1B multiplex assay

 Recommended
Concentration
Sample
Multiplex Capture3-20ug/mLRabbit anti-Human TNFRSF1B mAb(Cat. No.RMK0235)
Multiplex Detection0.017-2ug/mLRabbit anti-Human TNFRSF1B mAb(Cat. No.RMK0236)
Standard6.86-5000pg/mLRecombinant Human TNFRSF1B Protein

背景信息

The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.