产品和服务 / 产品类型 / ELISA试剂盒 / ELISA 抗体对
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Human TNFRSF1B multiplex assay
Recommended Concentration | Sample | |
---|---|---|
Multiplex Capture | 3-20ug/mL | Rabbit anti-Human TNFRSF1B mAb(Cat. No.RMK0235) |
Multiplex Detection | 0.017-2ug/mL | Rabbit anti-Human TNFRSF1B mAb(Cat. No.RMK0236) |
Standard | 6.86-5000pg/mL | Recombinant Human TNFRSF1B Protein |
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.