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* This package insert must be read in its entirety before using this product.
Human TNF-alpha Sandwich Immunoassay
Recommended Concentration | Sample | ||
---|---|---|---|
Multiplex | Capture | 0.1-5ug/mL | Rabbit anti-Human TNF-alpha mAb(Cat. No. RMK0416) |
Detection | 0.5-2ug/mL | Rabbit anti-Human TNF-alpha mAb(Cat. No. RMK0436) | |
Standard | 6.86-5000pg/mL | Recombinant Human TNF-alpha Protein (Cat. No. RP00001) |
Tumor necrosis factor, or TNF alpha, is a cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. Furthermore, TNF alpha is a ligand of the TNF superfamily which plays a central role in inflammation, apoptosis, proliferation, invasion, angiogenesis, metastasis, and morphogenesis. It is mainly secreted by macrophages, and can induce cell death of certain tumor cell lines. Rat and Human TNF alpha are 95% and 79% identical to Mouse TNF alpha, respectively.